Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2 |
| Enrichment Score (ES) | -0.73083055 |
| Normalized Enrichment Score (NES) | -2.0636113 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0029123202 |
| FWER p-Value | 0.014 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PPP2R5D | 1450560_a_at | 1667 | 2.413 | -0.0346 | No | ||
| 2 | FZD1 | 1422985_at 1437284_at | 3648 | 1.423 | -0.1006 | No | ||
| 3 | DKK2 | 1420512_at | 4198 | 1.288 | -0.1035 | No | ||
| 4 | DKK1 | 1420360_at 1458232_at | 7798 | 0.737 | -0.2551 | No | ||
| 5 | WIF1 | 1425425_a_at | 9208 | 0.561 | -0.3098 | No | ||
| 6 | WNT1 | 1425377_at | 10816 | 0.381 | -0.3766 | No | ||
| 7 | PROC | 1418845_at 1444979_at | 11471 | 0.306 | -0.4012 | No | ||
| 8 | PITX2 | 1424797_a_at 1450482_a_at | 11687 | 0.286 | -0.4060 | No | ||
| 9 | NKD2 | 1419465_at 1419466_at | 13221 | 0.116 | -0.4740 | No | ||
| 10 | CTNNB1 | 1420811_a_at 1430533_a_at 1450008_a_at | 17618 | -0.827 | -0.6604 | No | ||
| 11 | HDAC1 | 1448246_at | 17717 | -0.867 | -0.6500 | No | ||
| 12 | DVL1 | 1437301_a_at 1450978_at | 19489 | -1.765 | -0.7005 | Yes | ||
| 13 | LRP6 | 1451022_at | 19502 | -1.774 | -0.6706 | Yes | ||
| 14 | LDB1 | 1452024_a_at | 20278 | -2.445 | -0.6640 | Yes | ||
| 15 | LEF1 | 1421299_a_at 1436398_at 1440760_at | 20367 | -2.555 | -0.6242 | Yes | ||
| 16 | TRRAP | 1416532_at | 20649 | -2.946 | -0.5864 | Yes | ||
| 17 | FRAT1 | 1449814_at | 20668 | -2.972 | -0.5362 | Yes | ||
| 18 | EP300 | 1434765_at | 20959 | -3.504 | -0.4893 | Yes | ||
| 19 | AXIN1 | 1426966_at 1426967_at 1441029_at | 21136 | -3.874 | -0.4308 | Yes | ||
| 20 | CREBBP | 1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at | 21224 | -4.102 | -0.3644 | Yes | ||
| 21 | CSNK2A1 | 1419034_at 1419035_s_at 1419036_at 1419037_at 1419038_a_at 1453427_at | 21816 | -7.560 | -0.2616 | Yes | ||
| 22 | CCND2 | 1416122_at 1416123_at 1416124_at 1430127_a_at 1434745_at 1448229_s_at 1455956_x_at | 21833 | -7.719 | -0.1298 | Yes | ||
| 23 | GSK3B | 1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at | 21861 | -7.833 | 0.0034 | Yes |
